Catalogue
6
curated protein monographs
Evidence
56
citations across the library
Focus
Sequence → function
map sequence variation to therapeutic relevance
Featured Article
APOE
APOE
Apolipoprotein E (APOE) is a key protein involved in lipid transport and metabolism, with significant implications for aging, neurodegenerative disease, and longevity. The APOE gene has three common alleles—ε2, ε3, and…
Protein Library
CCR1
CCR1
CCR1 is a chemokine receptor involved in immune cell migration and inflammation. While direct evidence linking CCR1 sequence modifications to longevity is absent in the provided data, its role in immune regulation and…
Read articleCCR2
CCR2
CCR2 is a chemokine receptor involved in immune cell migration and inflammation. It binds to chemokines such as CCL2 (MCP-1) and plays a role in various diseases including HIV, cardiovascular disorders, and…
Read articleCCR5
CCR5
C-C chemokine receptor type 5 (CCR5) is a protein encoded by the CCR5 gene, located on chromosome 3 (3p.21.31). It functions as a co-receptor for HIV-1 entry into host cells, particularly R5-tropic strains. CCR5 is also…
Read articleCCR7
CCR7
CCR7 is a chemokine receptor involved in the trafficking of immune cells, particularly T cells and dendritic cells, to secondary lymphoid organs. It plays a critical role in adaptive immunity and immune surveillance.…
Read articleGANAB
GANAB | Glucosidase II Alpha Subunit
## Metadata
Read article